Ƙimar bayyanar da sana'a zuwa 4,4'-methylene-bis- (2-chloroaniline) "MOCA" ta hanyar sabuwar hanya mai mahimmanci don kula da ilimin halitta

Hanyar nazari na labari, wanda ke da ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun ƙayyadaddun hankali da ƙwarewa mai ƙarfi, an sami nasarar haɓaka shi don ƙayyade 4,4'-methylene-bis-(2-chloroaniline), wanda aka fi sani da "MOCA," a cikin fitsarin ɗan adam. Yana da mahimmanci a lura cewa MOCA wani ƙwayar cuta ce mai kyau da aka rubuta, tare da kafaffen shaidar toxicological da ke tabbatar da cutar kansa a cikin dabbobin dakin gwaje-gwaje kamar berayen, beraye, da karnuka.

Kafin amfani da wannan sabuwar hanyar da aka haɓaka a cikin saitunan sana'a na zahiri, ƙungiyar bincike ta fara gudanar da wani ɗan gajeren nazari na farko ta amfani da berayen. Babban makasudin wannan binciken na yau da kullun shine don ganowa da bayyana wasu mahimman abubuwan da ke da alaƙa da haɓakar fitsari na MOCA a cikin ƙirar dabba-ciki har da abubuwan da suka haɗa da ƙimar haɓaka, hanyoyin rayuwa, da taga lokaci don matakan ganowa- aza ingantaccen tushe na kimiyya don aikace-aikacen gaba na hanyar a cikin samfuran ɗan adam.

Bayan kammalawa da kuma tabbatar da binciken na yau da kullun, an yi amfani da wannan hanyar gano fitsari bisa ƙa'ida don tantance girman faɗuwar sana'a ga MOCA tsakanin ma'aikata a masana'antar Faransa. Matsakaicin binciken ya ƙunshi nau'ikan nau'ikan yanayin aiki guda biyu waɗanda ke da alaƙa da MOCA: ɗayan shine tsarin samar da masana'antu na MOCA kanta, ɗayan kuma shine amfani da MOCA azaman wakili mai warkarwa a cikin masana'antar elastomer na polyurethane, yanayin aikace-aikacen gama gari a cikin sinadarai da masana'antu.

Ta hanyar gwaje-gwaje masu yawa na samfuran fitsari da aka tattara daga ma'aikata a cikin waɗannan al'amuran, ƙungiyar bincike ta gano cewa matakan fitar da fitsari na MOCA sun nuna bambancin bambancin. Musamman, abubuwan da aka fitar sun fito ne daga matakan da ba za a iya gano su ba-wanda aka bayyana a matsayin ƙasa da 0.5 microgram a kowace lita-zuwa iyakar 1,600 micrograms kowace lita. Bugu da ƙari, lokacin da N-acetyl metabolites na MOCA ya kasance a cikin samfurori na fitsari, yawancin su sun kasance akai-akai kuma suna da ƙasa da yawa fiye da abubuwan da ke cikin mahaifa (MOCA) a cikin samfurori guda ɗaya, yana nuna cewa MOCA kanta ita ce nau'i na farko da aka fitar a cikin fitsari da kuma mafi yawan abin dogara mai nuna alama.

Gabaɗaya, sakamakon da aka samu daga wannan babban kima na fallasa ayyukan sana'a ya bayyana daidai da daidai daidai da daidaitattun matakan bayyanar MOCA na ma'aikatan da aka bincika, yayin da matakan fitar da aka gano suna da alaƙa da yanayin aikinsu, tsawon lokacin fallasa, da yanayin yanayin aiki. Bugu da ƙari kuma, wani muhimmin abin lura daga binciken shi ne cewa bayan an kammala ƙaddarar ƙididdiga kuma an aiwatar da matakan rigakafin da aka yi niyya a cikin wuraren aiki-kamar inganta tsarin iska, haɓaka amfani da kayan kariya na sirri (PPE), ko inganta ayyukan tsari-matakin fitar da fitsari na MOCA a cikin ma'aikatan da abin ya shafa sukan nuna raguwa a fili da kuma hana raguwa, yana nuna tasiri na MOCA.